Editorial commentary: Progesterone and spermatozoa: a long-lasting liaison comes to definition

Progesterone receptors on human spermatozoa.

Progesterone, primarily recognized as a female steroid hormone, is reported to affect several sperm functions especially capacitation, motility and acrosome reaction. These effects of progesterone on the spermatozoa are mediated via the progesterone binding sites/progesterone receptor (PR) on the acrosomal membrane. These receptors in response to progesterone increase the intercellular Ca2+ lev...

Commentary: Automation comes of age

The publishing of this Journal represents the beginning of the end; the end of a struggle to legitimise automation in chemistry and the beginning of what trust will be a valuable means of communication for those of us, as chemists, who become increasingly involved with automatic analysis. Automation can be defined in many ways but should not be used simply to imply mechanisation of a single fac...

Editorial Commentary

Socioeconomic status (SES) is a known risk factor for cardiovascular disease.1,2 However, unlike traditional Framingham risk factors, SES does not directly impact the cardiovascular system but exerts its cardiovascular effects via a complex interaction of biobehavioral factors, such as exercise and diet (Figure). Because these mediating behavioral factors are potentially modifiable, elucidating...

Long-Lasting Protective Immunity to

Effects of cryo-injury on progesterone receptor(s) of canine spermatozoa and its response to progesterone.

The integrity of sperm progesterone (P4) receptor(s) and its response to steroid stimulation might be crucial for the maintenance of sperm fertilizing ability after cryopreservation. The aim of the current investigation was to study the effect of cryo-procedures on canine sperm P4 receptor(s). In addition, alteration of P4 receptor(s) at the molecular level and their functional integrity follow...